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Do they usually have diseases? Which disease is the most fatal? What are the signs and symptoms of the disease?
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The most common disease in cats is feline immunodeficiency virus ( FIV) which affects the red blood cells of cats. Characterized with vomiting, lethargy, aggressiveness, lack of appetite, and inactivity among other symptoms.
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How fatal is this disease? Does it usually kill them?
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The most common diseases in cats are the Feline-immunodeficiency-virus SHORTLY (FIV) which creates affects the red blood cells

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Sounds like HIV to me. Is it as fatal as HIV? But it affects red blood cells.

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