Question

Almost all calico cats are female?

Answer 1

Yes, almost all calico cats are female. This is because the gene for the calico coat pattern is located on the X chromosome, and females have two X chromosomes while males have only one. As a result, males are much less likely to have the gene for the calico coat pattern.

Answer 2

Because the genetic determination of coat colors in calico cats is linked to the X chromosome, calicoes are nearly always female, with one color linked to the maternal X chromosome and a second color linked to the paternal X chromosome.