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What breed of cat is almost always female?
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3 Answers

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The Sphynx breed of cat is almost exclusively female. This breed is known for its hairless, wrinkled skin and its friendly, outgoing personality.
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Calico cats are almost always female because the locus of the gene for the orange/non-orange coloring is on the X chromosome.
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Calico cats are almost always female. The genes responsible for the calico coloration are linked to the X chromosome, and females have two X chromosomes (XX), allowing for the expression of the calico pattern. Male calico cats are rare and usually have XXY chromosomes.
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